LAND RIGHTS AND INTRA-HOUSEHOLD EMPLOYMENT AND RESOURCE USE IN THE PERI-URBAN AREA OF BANJUL, THE GAMBIA

As part of cooperative research program examining factor markets in peri-urban areas of The Gambia (Banjul and Serekunda) to see if they are constraining agricultural growth and employment, particularly in the horticultural subsector, the household production survey reported in this study assesses inter- and intrahousehold issues of market access and constraints to land-improving investment and productivity. Implemented in 1993, survey is highly disaggregated by plot, gender, enterprise, and type of employment.Land tenure--Gambia--Banjul Region, Vendors and purchasers--Gambia--Banjul Region, Household production--Gambia, Research methods, Rural conditions--Gambia, Rural off-farm employment--Gambia, Income and wealth--Gambia, Land markets--Gambia, Tenure types, Traditional--Gambia, Labor and Human Capital, Land Economics/Use,

Pharmacology of airway afferent nerve activity

Afferent nerves in the airways serve to regulate breathing pattern, cough, and airway autonomic neural tone. Pharmacologic agents that influence afferent nerve activity can be subclassified into compounds that modulate activity by indirect means (e.g. bronchial smooth muscle spasmogens) and those that act directly on the nerves. Directly acting agents affect afferent nerve activity by interacting with various ion channels and receptors within the membrane of the afferent terminals. Whether by direct or indirect means, most compounds that enter the airspace will modify afferent nerve activity, and through this action alter airway physiology

Racial Disparities in Intravenous Recombinant Tissue Plasminogen Activator Use Persist at Primary Stroke Centers.

BACKGROUND: Primary stroke centers (PSCs) utilize more recombinant tissue plasminogen activator (rt-PA) than non-PSCs. The impact of PSCs on racial disparities in rt-PA use is unknown. METHODS AND RESULTS: We used data from the Nationwide Inpatient Sample from 2004 to 2010, limited to states that publicly reported hospital identity and race. Hospitals certified as PSCs by The Joint Commission were identified. Adults with a diagnosis of ischemic stroke were analyzed. Rt-PA use was defined by the International Classification of Diseases, 9th Revision procedure code 99.10. Discharges (304 152 patients) from 26 states met eligibility criteria, and of these 71.5% were white, 15.0% black, 7.9% Hispanic, and 5.6% other. Overall, 24.7% of white, 27.4% of black, 16.2% of Hispanic, and 29.8% of other patients presented to PSCs. A higher proportion received rt-PA at PSCs than non-PSCs in all race/ethnic groups (white 7.6% versus 2.6%, black 4.8% versus 2.0%, Hispanic 7.1% versus 2.4%, other 7.2% versus 2.5%, all P CONCLUSIONS: Racial disparities in intravenous rt-PA use were not reduced by presentation to PSCs. Black patients were less likely to receive thrombolytic treatment than white patients at both non-PSCs and PSCs. Hispanic patients were less likely to be seen at PSCs relative to white patients and were less likely to receive intravenous rt-PA in the fully adjusted model

Profound Learning and Living: An Exploratory Delphi Study

This study, using Delphi methodology conceptualizes the qualities of profound learning, the profound learner, and profound living

Mass Spectrometry-based Methods for Phosphorylation Site Mapping of Hyperphosphorylated Proteins Applied to Net1, a Regulator of Exit from Mitosis in Yeast

Prior to anaphase in Saccharomyces cerevisiae, Cdc14 protein phosphatase is sequestered within the nucleolus and inhibited by Net1, a component of the RENT complex in budding yeast. During anaphase the RENT complex disassembles, allowing Cdc14 to migrate to the nucleus and cytoplasm where it catalyzes exit from mitosis. The mechanism of Cdc14 release appears to involve the polo-like kinase Cdc5, which is capable of promoting the dissociation of a recombinant Net1·Cdc14 complex in vitro by phosphorylation of Net1. We report here the phosphorylation site mapping of recombinant Net1 (Net1N) and a mutant Net1N allele (Net1N-19m) with 19 serines or threonines mutated to alanine. A variety of chromatographic and mass spectrometric-based strategies were used, including immobilized metal-affinity chromatography, alkaline phosphatase treatment, matrix-assisted laser-desorption post-source decay, and a multidimensional electrospray mass spectrometry-based approach. No one approach was able to identify all phosphopeptides in the tryptic digests of these proteins. Most notably, the presence of a basic residue near the phosphorylated residue significantly hampered the ability of alkaline phosphatase to hydrolyze the phosphate moiety. A major goal of research in proteomics is to identify all proteins and their interactions and post-translational modification states. The failure of any single method to identify all sites in highly phosphorylated Net1N, however, raises significant concerns about how feasible it is to map phosphorylation sites throughout the proteome using existing technologies

Science and the IS Researcher: Building an Empire Without Walls

The purpose of this paper is to introduce a radical alternative perspective into the debate on diversity, and the use of reference disciplines in IS research. It seeks to provide the foundation for a philosophical dialectic from which a new synthesis of the opposing views on the debate may emerge. Specifically, it is argued that the boundaries that divide academic disciplines are merely social conventions; products of convenience and individual and group self-interest. In contrast to this socially constructed view of scholarly inquiry, it is argued thatscience is a common good and that maturity of a field and of a researcher is evidenced not by defending the walls of a scientific empire but by contributing to the broader scientific community in which scholars in all fields may participate. The paradigm promulgated here is one of intellectual development and knowledge sharing that breaks down the walls of disciplines, views knowledge holistically, and considers the spread and evolution of ideas as the most important goal of all researchers. More than justa philosophical ideal, with the advent of the world wide web this new paradigm becomes a very real possibilit

Conceptualizing An Abundance Mentality and Its Relationship to Lifelong Learning, Human Flourishing, and Profound Learning

The purpose of this exploratory literature review is to describe and continue to develop the concept of an abundance mentality and how it relates to lifelong learning, human flourishing, and profound learning

eBank UK: linking research data, scholarly communication and learning

This paper includes an overview of the changing landscape of scholarly communication and describes outcomes from the innovative eBank UK project, which seeks to build links from e-research through to e-learning. As introduction, the scholarly knowledge cycle is described and the role of digital repositories and aggregator services in linking data-sets from Grid-enabled projects to e-prints through to peer-reviewed articles as resources in portals and Learning Management Systems, are assessed. The development outcomes from the eBank UK project are presented including the distributed information architecture, requirements for common ontologies, data models, metadata schema, open linking technologies, provenance and workflows. Some emerging challenges for the future are presented in conclusion